SLGP Header

Evaluation of Antimicrobial Activity of Indian Nettle, Acalypha Indica

jasem Front Page
Acalypha indica is a species of plant having catkin type of inflorescence. It occurs throughout tropical Africa and South Africa, in India and Srilanka, as well as in Yemen and Pakistan. This plant is held in high esteem in traditional tamil siddha medicine as it is believed to rejuvenate the body. Pharmacological investigation has shown that the plant has potent antibacterial, antifungal, anti – inflammatory, anti – osteoporotic, antioxidant, neuro protective, wound healing, post – coital antifertility activities. The present work is aimed to evaluate the antimicrobial activity of Acalypha indica leaf extract. Antibacterial activity is studied against strains Staphylococcus aureus, Escherichia coli, Salmonella typhi, Bacillus and Pseudomonas aeruginosa. We got maximum zone of inhibition of 13mm for Staphylococcus aureus and minimum zone of inhibition of 7mm for Escherichia coli. Antifungal activity is studied against species Rhizopus microsporus, Candida albicans, Aspergillus niger and Trichoderma viride We got maximum zone of inhibition of 10mm for Rhizopus microsporus and minimum zone of inhibition of 8mm for Aspergillus niger.

Keywords:Acalypha indica, antibiotics, antimicrobial


  1. Ahmad, Z., Mehrdad. I., Shahabudin, G. and Zahra, R. “Investigation of antibacterial effects of garlic (Allium sativum), mint (Menthe spp.) and Onion (Allium cepa) herbal extracts on Escherichia coli isolated from broiler chickens”. African Journal of Biotechnology. Vol. 10(50), pp. 10320 –10322, 2011.
  2. Anbukkarasi, M. “A study on antimicrobial activity of Acalypha indica crude extraction of methanolic compound”. International Journal of Current science, pp. 282 – 286, 2012.
  3. Apurbokumar, S., Md. Rashidur, R., Masumshahriar, Sudipkumar, S., Nadezda Al Azad and Susmiti, D. “Screening of six Ayurvedic Medicinal plant Extracts for Antioxidant and cytotoxic activity”. Vol. 2(2), pp. 181 – 188.
  4. Arora, S., Kaur, K. and Kaur, S. “Indian medicinal plants as a reservoir of protective phytochemicals”. Terat Carcinogen Mutagen. Vol. 1, pp. 295 – 300, 2003.
  5. Basheer, A., Al – Sum., Abdullah, A and Arfaj, Al. “Antimicrobial activity of the aqueous extract of mint plant”. Science Journal of Clinical Medicine, Vol. 2 (3), pp. 110 – 113, 2013.
  6. Durga, K.R. Karthikumar, S. and Jagadeesan, K. “Isolation of Potential antibacterial and antioxidant compounds from Acalypha indica and Ocimum basilicum”. Journal of Medicinal plants Research. Vol. 3(10), pp. 703 – 706, 2009.
  7. Farah, D., Siti, Z. Mat, S., Anis, H. Asmali, J., Nini, N.N. and Norazian, M. H. “In vitro study of Antimicrobial activity of Acalypha indica Linn. Extract”. The Open Conference Proceedings Journal, Vol. 4, pp. 57 – 60, 2013.
  8. Goplakrishnan, V., Rao.K.N.V., Loganathan, V., Shanmuganathan, , BolluV.K and Bhavanasarma, T. “Antimicrobial activity of extracts of Acalypha indica Linn”. Indian Journal of Pharmaceutical sciences, Vol. 65(5), pp. 347 – 350, 2000.