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A new empirical model to correlate solubility of pharmaceutical compounds in supercritical carbon dioxide

jasem Front Page
Author(s):
Tippana Ashok Reddy, R.Srividya,Chandrasekhar Garlapati
Volume
4, No.2
Pages:
575-590
Year of Publication:
August, 2018
Journal of Applied Science and Engineering Methodologies
ISSN:
2395–5341
Citation: Tippana Ashok Reddy, R.Srividya,Chandrasekhar Garlapati."A new empirical model to correlate solubility of pharmaceutical compounds in supercritical carbon dioxide." Journal of Applied Science and Engineering Methodologies4.2 (2018):575-590. Article ID 42575590. BibTex

@article{2018anew590, author = {Tippana Ashok Reddy, R.Srividya,Chandrasekhar Garlapati}, title = {A new empirical model to correlate solubility of pharmaceutical compounds in supercritical carbon dioxide}, journal = {Journal of Applied Science and Engineering Methodologies}, issue_date = {25}, volume = {4}, number = {2}, month = {Aug}, year = {2018}, issn = {2395–5341}, url = {http://www.jasem.in/2018/42575590.html}, publisher = {Journal of Applied Science and Engineering Methodologies}, address = {Chennai, India} }

DOI:
Abstract:
The objective of the current research is to propose a new empirical model to correlate solubility of pharmaceutical drug compounds in supercritical carbon dioxide. The predictive ability of the new model is validated with literature data. In this work twenty-seven industrially important pharmaceutical compounds are considered for the validation. The correlative accuracy of the model is evaluated in terms of absolute average relative deviation.

Keywords:Degree of Freedom, New Empirical Model, Pharmaceutical, Solubility, Supercritical Carbon Dioxide.

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