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A new empirical model to correlate solubility of pharmaceutical compounds in supercritical carbon dioxide

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The objective of the current research is to propose a new empirical model to correlate solubility of pharmaceutical drug compounds in supercritical carbon dioxide. The predictive ability of the new model is validated with literature data. In this work twenty-seven industrially important pharmaceutical compounds are considered for the validation. The correlative accuracy of the model is evaluated in terms of absolute average relative deviation.

Keywords:Degree of Freedom, New Empirical Model, Pharmaceutical, Solubility, Supercritical Carbon Dioxide.


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